From the Ming Dynasty to 2050

During the Wanli reign of the Ming dynasty, Yun Zhi, a female physician at the Imperial Medical Academy, accidentally triggers a mysterious device while investigating a strange plague in the imperial family and is transported to the year 2050. In this future, where technology has advanced dramatically but a new kind of brain plague threatens humanity, she meets Qi Yang, a scientist devoted to brain research ever since his parents disappeared.

When Yun Zhi's ancient medical knowledge sparks against modern technology, the two gradually discover that her transmigration was no accident. A multinational corporation called “New Era” is secretly conducting experiments in time and space, hoping to alter the course of history. Even more shocking, Qi Yang's parents' research is inextricably linked to Yun Zhi's journey through time.

From the bustling cities of the future to virtual data worlds, from the secrets of the Ming dynasty court to scientific breakthroughs that could change humanity's fate, Yun Zhi and Qi Yang must find each other in the maze of time and space and unravel a mystery four hundred years in the making. As the truth gradually comes to light, they face a difficult choice: should Yun Zhi return to her own era, or should they join forces to prevent a temporal catastrophe capable of overturning human history?