[Physics and Chemistry Power Fantasy (?)]
Using atoms and all kinds of chemical elements for cultivation
The protagonist's career arc is about synthesizing atoms and molecules into organic and inorganic compounds to cultivate immortality.
Romance: A gloomy, destructive top who thinks about ending the world all day x an optimistic, energetic, endlessly curious bottom who loves causing trouble
For the world-ending premise, I want a Phineas and Ferb kind of feel. The bottom synthesizes elements and comes up with all sorts of schemes that happen to collide with the top's world-ending antics and cancel them out, so nothing happens.
Theme: Study hard and improve every day