When college student Chen Mo's parents uncover the secrets of an ancient Godslayer legacy and an evil god's seal, business tycoon Zhao Tianze frames him for murdering his own parents. Drugged and sent to a psychiatric hospital, Chen Mo suffers endless humiliation. On the brink of death, he activates the God-Tier Godslayer Sign-In System and awakens the bloodline and memories of an ancient Godslayer.
With the System's rewards, Chen Mo kills his enemies' henchmen inside the hospital, exposes the director's plot, and meets the previous generation's guardian, “Old Ghost,” who has been disguised as a janitor. He learns that he is the reincarnation of the Godslayer leader who sealed the evil god a thousand years ago, and that Zhao Tianze is actually the evil god's lackey, plotting to break the seal and bring calamity upon the world.
Chen Mo joins forces with Su Wanqing, a female captain from the Paranormal Affairs Bureau who has come to investigate supernatural incidents. He exposes Zhao Tianze's identity as a practitioner of demonic arts before a crowd and kills him, acquiring the first divine artifact fragment, the Guardian Seal, and uniting Jiangcheng's cultivation world. But Zhao Tianze's death sets off an even greater crisis: the evil god's four great guardians awaken, and seals at sites across the country begin to weaken.
To face the nationwide crisis, Chen Mo repels the Black Wind Guardian, who comes to assassinate him, then rushes back to help Jiangcheng overcome a tide of demons. Accompanied by his master, Old Ghost, and his comrade Su Wanqing, he heads to the capital at the government's invitation. His new mission is to unite cultivators across the country, form an alliance, gather the divine artifact fragments, and oppose the evil god's forces as they fully revive, protecting peace in the mortal world.
