I've read a lot of crossover novels set in the Marvel and DC universes lately, and I have a few ideas I hope I can write down.
Isabel lived in the best of times and the worst of times. Later, she was seen as a disaster. Later, she lost her loved ones. Later, she kept living with hope in her heart, then fell asleep.
When she woke up, the world seemed unchanged. She left again, met some friends, and received guidance.
When she woke up once more, the world seemed different. Life had become much more exciting, and at last she no longer had regrets.
(I originally planned to write this in more detail, but the more I wrote, the less inspired I felt. So I sketched out a rough outline instead. Still, it's easy enough to follow.)
Theme: Changing a tragic ending.
In fact, Thor is not particularly stupid, he is just reckless.