Luo Shao, a poison doctor, transmigrates into a world inside a book that blends an ancient romance with the rules of a sci-fi apocalypse. She's also bound to Yan Fu, her childhood sweetheart who grew up with her at school. One is an expert at concocting every kind of poison and its antidote; the other can cook old-fashioned dishes that soothe the restless emotions of those with supernatural abilities. Together, they break free of their fated tragic ending, build a safe haven amid treacherous calamities, and rewrite the original story's conclusion in which everyone perishes.