A premeditated siege brought the Guan clan to ruin. Only the eldest daughter, Guan Zhiying, escaped. She later married Mu Yu, crown prince of Nanping, as a secondary consort, but died in childbirth a year later.
From then on, the Guan clan vanished without a trace.
Eighteen years later, A Qi, a sixteen-year-old physician at Prince Ying's residence, is accidentally drawn into the Guan clan's generations-old feud. Together with Mu Linyu, Prince Ying of Nanping, she searches for the truth behind the clan's destruction eighteen years ago.