Ke Xin and Juzi, sisters from a rural family, are obedient, sensible, and hard-working students. At last, they receive the university admission letters they had long hoped for and enter campus full of excitement, only to be assigned to Dorm Room 401 by an unexpected twist of fate. They know nothing of the bloody past haunting the room.
A year earlier, a senior student in a red dress, on the verge of graduation, was abandoned after her relationship fell apart. Wearing the red wedding dress her boyfriend had given her, she leapt in despair from the window of Dorm Room 401. She hit the concrete ground headfirst, her blood and brains splattering everywhere. She died on the spot. Her resentment lingered in the dorm, while the bloodstains on the windowsill and the blood-soaked red wedding dress became vessels for her obsession.
The sisters, who have only each other to rely on, push open the door to Room 401 without a clue what awaits them. A bloody nightmare for the start of the school year quietly begins.