Su Nian, a brilliant modern-day surgeon, transmigrates into the 1970s as a pregnant educated youth, isolated and helpless, with her reputation in tatters and her family driving her into a corner.
To protect herself, she boldly proposes a whirlwind marriage to Lu Jianguo, the rough, lone-wolf bachelor whom everyone in the village fears.
She thinks she is only finding temporary protection, but this fearsome man, whose background is shrouded in mystery, ends up treating her like a queen.
With silver needles in one hand and a scalpel in the other, Su Nian thrives as she takes down villains, makes them eat their words, and saves lives. The pharmaceutical company she founded, Niankang Pharmaceuticals, is about to change the times.
Meanwhile, Lu Jianguo, who seems like an ordinary man, gradually reveals his hidden ties to a powerful family in the capital.
See how this young couple build their careers in the 1970s and raise their adorable babies, a set of twins, as they journey from the countryside to the top of the world!