When investigating the reanimation of corpses in Yinshan Village, Su Yuan, a Maoshan Heavenly Master, accidentally absorbs the essence blood of Jiang Chen, the progenitor of zombies, and is forced down a bizarre path, half human and half corpse. He uses the Scripture of Supreme Purity on Corpse Liberation to suppress the corpse poison while investigating the mastermind behind it all: Xu Fu, a Qin Dynasty alchemist with a world-ending conspiracy. Xu Fu plans to use Jiang Chen's bloodline to resurrect Qin Shi Huang and build a zombie empire. To that end, he has laid the groundwork for a global “Blood Moon Project,” igniting a war between monsters of the East and West.
As the corpse poison spreads, Su Yuan gradually awakens the ability to control blood, but also struggles with his craving for human blood and the fight to hold on to his humanity. Alongside Ma Dingdang, an heir to a clan of exorcist dragon hunters, and his junior sister Lin Ruoxue, he forms an exorcist squad and battles vampires, swarms of corpse beetles, and half-blood zombies in Hong Kong, western Hunan, Kunlun, and elsewhere. Meanwhile, Jiang Chen lurks among humanity under the identity of antique dealer Jiang Zhenzu. Though he appears to be bringing about the apocalypse, he harbors a deeper aim: to break the shackles of fate binding the Pangu clan.
As Nuwa's primordial spirit returns and an asteroid crisis looms, Su Yuan faces the ultimate choice: follow Jiang Chen's plan for “corpse liberation and rebirth,” freeing humanity from fate but turning it into a race of zombies, or wield himself as a sword, shatter Nuwa's primordial spirit, and fall into the Abyss forever. What he doesn't know is that every choice he makes is uncovering a thousand-year-old truth about the secret Maoshan scriptures and the Pangu clan's creation of the world... I defy fate with my essence blood, and laugh as I watch the ages pass beneath the autumn sky.
