Political infighting driven by extreme ideologies and globalization marks a major turning point in American politics. The Democratic Party scored sweeping victories in presidential and congressional elections, and gained the upper hand in most ideological arenas, bringing a dramatic shift in the political landscape. Although America’s constitutional system can still resolve ordinary political crises, the country’s ideological polarization has undeniably reached an irreconcilable point. As the world’s superpower, the United States has long promoted economic globalization, yet globalization has clearly diminished its influence around the world, while domestic politics have descended into unprecedented turmoil. The dramatic turning point in American domestic politics, along with the shifting balance in US-China relations, will reshape the geopolitical map of the world.