In the late Qing dynasty, Yi Chunye's dearest wish is to hang up the sign for her family's Chinese medicine shop, Yihetang, once again.
While meditating, her soul leaves her body and travels to the year 2106.
The venerable Li Hongfei has attained immortality and still resides in the immortal grotto of Longevity Cave.
Under the assumed name Yi Xiayue, Chunye joins the Luo family as an intern and falls in love with Luo Yan, the family's son.
After uncovering a century-old feud between the Yi and Luo families, she finds the venerable master and returns to the late Qing dynasty to continue her cultivation.
With disaster gripping the nation, the venerable master secretly helps Yi Xiayue return to the modern era, where she and Luo Yan work together to develop a medicinal formula.
Luo Yan: Let me go back with you to the late Qing dynasty and live in seclusion in the mountains.
Xiayue: When the clouds drift across the empty sky, I realize I have never left your side.
Luo Yan: I believe that one day, even if everyone around us opposes our being together, I will still send eight sedan bearers to carry you into the Luo family as my bride.
