This is a modern-day transmigration mythological comedy. It tells the moving story of a young man studying traditional Chinese medicine who accidentally transmigrates to another era. After a chance encounter with love and a realization that life is short, he struggles relentlessly in pursuit of love and longevity.
The protagonist, Chen Tianming, lost his mother when he was young and was raised by his father. He comes from a family of traditional Chinese medicine practitioners, and under his father's influence, he developed an exceptional talent for medicine from an early age. After arriving in another era, he receives the inheritance of a master alchemist. When he finally leaves the place where the inheritance was passed down, he meets the other most important person in his life: his wife, Bai Ruxue.
Bai Ruxue is the only daughter of a dynasty's chancellor. After her father and family are implicated in the crimes of corrupt officials, she escapes the capital with only a small group of servants and guards. After enduring many hardships, Bai Ruxue and Chen Tianming meet by chance.
With Chen Tianming's help, Bai Ruxue succeeds in avenging her father. But their happy days do not last. To hold on to time, Chen Tianming decides to defy fate and change his destiny. After countless opportunities, trials, and brushes with death, he finally manages to ascend to immortality...