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Shen Qingyuan, the chief medical and poisoner in the 25th century, accidentally traveled through time and became a good-for-nothing legitimate daughter who was bullied by others in the Prime Minister's Palace. She was plotted by her concubine and concubine to marry the disabled and violent King Xiao Yeheng. She possesses peerless medical poison skills, which can not only revive human flesh and bones, but also inflict invisible poison. After entering the palace, she gained a foothold with her medical skills, cured King Rui's leg disease, counterattacked the enemy with poisonous techniques, and reversed the situation step by step. The cold and violent King Rui was attracted by her intelligence and tenacity, and protected her with all his heart, and doted on her. The two worked together to break the conspiracy, resolve the situation, and finally amazed the government and the public, creating a legend of being both a doctor and a poisoner and an iron-blooded prince.