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Taking the Industrial Revolution as the background, this book uses interdisciplinary research methods to explore the process of cholera prevention and control in the UK from the perspective of environmental history. It focuses on combing the development and evolution of cholera prevention and control in the UK in the 19th century from the traditional isolation of patients to the treatment of "social diseases", and then to the treatment of "environmental diseases". It also analyzes the inherent tensions and gains and losses between this conceptual change and policy evolution, thereby three-dimensionally showing the tortuousness and complexity of cholera prevention and control in the UK. It is believed that the success of cholera prevention and control in the UK is the result of the joint efforts of the government, local cooperation, social support, concept updates, and technological progress. Drawing a picture of the interaction between cholera, humans and the environment in the context of the Industrial Revolution is a useful exploration of disease research paradigms from the perspective of environmental history, and also provides a mirror for the harmonious coexistence of humans and nature.