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A highly respected old head nurse risked her life while rescuing a patient with leukemia complicated by tuberculosis who was suffocating due to aspiration of blood clots. Unfortunately, she died of an infectious disease. Ten years later, her daughter Han Meng inherited her mother's legacy and became a young nurse after graduating from the nursing major. There were two women and one man assigned to this hospital as nurses together with her. One of them was Yang Xuemei, the daughter of the infectious disease patient. The two young female nurses experienced misunderstandings, estrangements, conflicts, and in the subsequent nursing process of treating patients, they jointly experienced the thrilling tortuous experiences and the ups and downs of the nursing career. They also faced the little-known truth, goodness, beauty, falsehood, evil and ugliness between life and death. They gradually matured and were finally baptized by their own souls. They became a pair of good sisters and determined to follow Nightingale as an example to become good nurses that everyone trusts and respects.