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Professor Lu Wenji retired to study brain thinking problems at home, so he asked his assistant Mei Li to buy a Labrador dog Peddy for brain experiments. Mei Li lied that Peddie was pregnant and asked the professor to perform heart surgery first and then conduct experiments after the dog was born. While waiting for surgery in the hospital, the professor accidentally discovered a hidden living brain laboratory, and he was secretly imprisoned. Mei Li discovered that the professor was missing and contacted the professor through a portable walkie-talkie. With the help of private detectives Yohansheng and Peddy, she successfully rescued the professor.

Scientists have observed that a low-mass ancient black hole is about to encounter the Earth, which will cause unimaginable disasters to the Earth. Before the disaster, Professor Lu Wenji, an interstellar detective, proposed the "cat by the tail" method of changing its orbit by hitting the black hole. Later, it was discovered that the black hole was only the size of an atom, and this method failed. At the same time, riots also occurred on the earth, and society fell into chaos. On the day when the end came, people all regained their composure and quietly waited for the end to come. After the change in the gravitational field, the black hole was successfully captured by the earth and became part of the earth.

On the first day of the new year, Mei Li discovered a strange light somewhere in Qinghai. She took advantage of the old man's desire to travel and took Professor Lu Wenji to the Mahayana Temple where the strange light was emitted. By chance, she met Chen Feng, who was also attracted by the strange light and came here to do research for his graduation thesis. In the end, the wise Professor Lu Wenji solved the doubts in Meili and Chen Feng's minds.

She has a pure heart and does not admire wealth and honor, but she is forced into the palace as a concubine. The emperor hated the teasing of his concubines, so he pretended to be a fool in the name of concubine Qian, just to make money and pay off his debts and leave. But why does that bad guy who hates her always go against her, pay her money, throw her into the lotus pond in a small dark room, and let her be a shield?

Lu Wenji received a distress letter from London. The letter stated that Emma and her husband Berkson were discovered by mistake during a trip after hearing news from an interstellar smuggler. The smuggler wanted to kill him, but he only captured Berkson and disguised him as a robot. She sent a message to Emma asking her to rescue her husband. In desperation, Emma sent a letter of help to Professor Lu Wenji, the space detective. Professor Lu Wenji, who is full of sense of justice, and his assistant Mei Li, use special means to distinguish Berkson among hundreds of robots, rescue him, and catch the criminals in one fell swoop.

Mrs. Walton, who was over sixty years old, found Professor Lu Wenji and told Professor Lu Wenji that her son had rescued his colleagues during the crisis of the space station explosion. Before he could enjoy the honor of becoming a hero when he returned to Earth, he was sued for violating the law "prohibiting the transformation of people into machines." After hearing the whole story, Professor Lu Wenji decided to help Mrs. Walton win the lawsuit. In the end, Mrs. Walton rescued her son.

Professor Lu Wenji and his assistant Mei Li remodeled the Bird's Nest and started their journey across the galaxy. The two drove the newborn Bird's Nest to the vicinity of the Andromeda Nebula and discovered X-ray light. Professor Lu Wenji asked Meili to turn around and go back. Just when Meili was confused, the professor told Meili that they had encountered a black hole. At this time, the distress signal in the Bird's Nest rang. Lu Wenji turned on the distress signal and found a couple trapped in the black hole. He immediately launched a rescue, but in the end he was unable to withstand the cruelty of the universe. He watched the couple disappear into the black hole and become eternal shadows.

Professor Lu Wenji's assistant Meili wanted to write a book about the professor's three experiences on Mars. In the end, she only needed a photo of the professor to complete the book, so she went on a photography trip to Europe, taking pictures while traveling. At a beach in Italy, a girl with a prosthetic leg came to seek help from a professor. The professor put her in a taxi and left. Meili recorded the process through her camera. Unexpectedly, it was reported that there were many missing cases of foreign girls in the local area. The murderer has not yet been found. At this time, someone reported the case again. After comparison, one of the missing foreign girls was the girl Sashaer who asked the professor for help in the afternoon. The police found the photos taken by Meili in the afternoon and found strange phenomena on them. The professor combined the photos taken on the asteroid and analyzed them together. The professor identified the kidnapping suspects, who were the owners of Dahe Nightclub and his wife.

Lu Wenji, who was struggling to design a star language, was found by a desperate jeweler. The jeweler told about a "bizarre jewelry case" he had been involved in a few days ago and handed the pearl to Professor Lu Wenji for verification. After observing it, Lu Wenji discovered that this was not just a pearl, it was also a "star messenger" painted in the language of the planet. This discovery not only solved the jeweler's dilemma, but also helped the professor find the most suitable "star language".

Professor Lu Wenji and his assistant Mei Li went on a business trip to Salt Lake City in the United States. They were accidentally arrested as terrorists who wanted to cause an explosion. After solving the misunderstanding, they were invited to investigate a strange explosion site. After on-site investigation, it was discovered that Dr. Ding was actually doing an experiment to add positrons to atoms. He was accidentally disturbed by Jesse, the policeman who broke in. Negative electrons were added to atoms, forming antimatter. In the energy release of the annihilation of matter and antimatter, both Dr. Ding and Jesse turned into silver figures.

A mysterious space visitor asked Professor Lu Wenji for help in space, but was mistaken by Professor Lu Wenji and his assistant Mei Li for a wanted space robber. After verification by Professor Lu Wenji through a series of scientific methods, it was discovered that the person asking for help was not a robber, which caused a joke.

Meili's uncle was sick, and the professor asked Meili to go back and take care of her uncle. Unexpectedly, a few days later, Meili brought her sick uncle to the space station and asked Lu Wenji to help solve a mysterious incident about the ancient battlefield of the Three Kingdoms in the water near the hydropower station. Lu Wenji took Meili and his uncle back to the Three Gorges and solved the problem.

Strange events such as the mysterious disappearance of aircraft and earthquakes on opposite sides of the earth have occurred one after another in the world. Professor Lu Wenji guessed that this was caused by the intersection of the anti-universe and the real universe. Everything in the anti-universe is opposite to the real universe, including time. This conjecture was proven based on analysis of scientific data from the space station and on Earth. The professor predicted that an anti-gravity field would arrive in the city soon, and Assistant Mei Li's plane would land at that time.

Professor Lu Wenji predicted that the focusing axis of the total galaxy will sweep through the solar system as the Milky Way rotates. At that time, the scene in the Milky Way in the distant past will be observed. However, due to the maintenance of the space station, he could not go to space for observation, so he and his assistant had to go to Hawaii to watch the sunset. Unexpectedly, at the home of a wealthy businessman, he used an amateur telescope to observe the scene of the Big Bang with his own eyes.

Nicholson of the Big Man Laboratory and the large accelerator in the laboratory mysteriously disappeared overnight. Cooper, the director of the laboratory, and Merson of the Counter-Terrorism Agency found Professor Luwenji in order to find the truth. At the same time, a young man came to the professor's house and claimed to study the mass of the universe. He discovered that in two hundred years, the universe had reduced the mass of a galaxy. Ruwenji dug deeper and guessed that the real purpose of this big laboratory was to study particle weapons. After analyzing its principles and comparing it with the young man's data, he calculated that the disappearance of Nelson and the accelerator was not an accident. It was all related to the origin and demise of the universe.

Hamilton's private research institute discovered a planet from outside the solar system in the asteroid belt. Hamilton and chemical analyst Mirante hoped to land on the planet to detect whether there were traces of life, so they found Professor Lu Wenji and his assistant Mei Li, and two assistants formed an expedition team to investigate the planet. On the planet, they discovered a highly evolved life form. Professor Lu Wenji communicated with it and learned about the magnificent process of life evolution and the mysteries of the universe. After returning to the spacecraft, it was discovered that the body of assistant Polo was filled with self-replicating alcohol, and his life was in danger. Everyone had to ask the alien life form for help, hoping to get help. At the same time, everyone also developed symptoms of alcohol upper body. In the end, with the help of the alien, the crisis was successfully resolved.

The time and space background of the Lu Wenji series is set in the not-too-distant future. The protagonists of the story are Professor Lu Wenji, an astronomer who has lived on the space station for many years and engaged in scientific research, and his assistant, the young and beautiful Miss Meili. The two protagonists have distinct personalities and reflect each other: Professor Lu Wenji is highly respected, rigorous, and well-educated, but has a somewhat eccentric temper and is even unkind; while Meili is an outgoing, sharp-tongued, and energetic young woman. Although the old man and the young man have very different personalities, they work together tacitly and have been friends for many years. It can be said that they are a quite happy couple. When this pair faces various mysteries, dangers and challenges, they can always rely on scientific wisdom to solve problems and turn danger into safety. It can be said that the author presents the sentence "knowledge is power" in front of readers with vivid story scenes.

During a panic trip, Professor Lu Wenji and Mei Li failed to catch up with the scheduled spaceship and lost their clothes. In order to rush for time, they had to change their tickets and board a civilian ship. However, because of the Coca-Cola advertising shirt they randomly wore during the trip, they were mistaken for the thief who stole the British Museum last night. In order to prove his innocence, Professor Lu Wenji launched a wise fight with the police, and finally helped the police catch the murderer.

Professor Lu Wenji discovered the ninth planet in the solar system by accident and calculated its orbit. At an international symposium on background radiation, Professor Lu Wenji, who was seeking funding, failed to seek help because of the other person's ridicule, so he made a bet with another professor. In the end, the stubborn and competitive old man Professor Lu Wenji discovered the ninth planet that had become a broken state through his own abilities. (In the 1990s, Pluto was considered the eighth planet.)

Professor Luwenji and his assistant Meili went to Alonika, Greece for a vacation. At night, they drove a yacht to the sea to observe comets, and unexpectedly heard the song of the legendary mysterious siren. The next day, the two of them went to the sea again with Jegu, who was pretending to be a waiter in the hotel, to search for the siren. This time they heard the same laughter in the performance of "Hamlet". On the way back, the three of them discussed the ins and outs of the matter. Yegu mentioned that there was a priest three hundred years ago, and his speech once spread throughout the streets and alleys of the city. After summarizing a series of things, Professor Luwenji discovered that it was all related to the curved stone wall in the square and the Comet Debro, which reincarnates once every sixty years.

The professor discovered that there was a position in the space station that the scientific community did not know yet. He came to the earth with questions and prepared to study with his old colleagues in the brain science field. However, he accidentally stayed in a haunted house and a series of strange things happened. Professor Lu Wenji and colleagues from the brain department teamed up to use scientific means to explain the stories that happened in the haunted house, helping the owner of the haunted house find his relatives and solve his own problems.