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Zhang Yingquan, who was born as a county magistrate, gave up his official position and became a doctor. He returned to his hometown of Xingzhou and founded Yuxing Tang. From Zhang Bingshan to Zhang Zaijing, and then to Zhang Guixin and Zhang Ziyu, generations of famous doctors in the Zhang family have been famous. Zhang Bingshan was extremely intelligent and became famous at a young age, but he was frail and sick. When he was dying, he was taken away by a Taoist priest with gray hair and childish face. It turned out that he was a Taoist and would definitely return to the Tao. Zhang Zaijing developed and expanded Yuxingtang, but he was involved in his relationship with Zhao Yushu. Zhao Yushu was originally the daughter of the Zhao family bone setting parlor. He was good at medicine and martial arts. He was good at court and fought gangsters. After becoming Zhang Zaijing's wife, he was willing to be the woman behind his back. Zhang Ziyu is gentle and beautiful, and has a good knowledge of Chinese and Western medicine, but her emotional journey is full of ups and downs. Facing her arbitrary father and wise lover, her heart is like a double mesh with thousands of knots in it. Song Baoliang, known as the weird doctor, was framed and imprisoned. He also wandered into Yuxing Hall and became a famous doctor there. The vicissitudes of the past century have changed the fate of the owners of Yuxing Hall. Love, family affection, friendship... Compose the ups and downs of the medical journey.