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Professor Wang, Louis, Teacher Zu, and Liu Fei - four young doctors of similar age but different personalities, came together because of their common medical philosophy, and were known as the "Four Elites in Emergency Medicine". They supported each other in the emergency room, rescuing patients from life and death together, and overcame various difficulties in the workplace together. Through the medical experience of making jokes, laughter and tears, they gradually grew into independent experts. In order to realize the ideal of treating diseases and saving lives and protecting the people, the four people established the private hospital "White Castle". While preparing to show off their talents, problems also came one after another: doctor-patient disputes, capital hijacking, villain framing, brotherly feud... In the game between ideal and reality, they finally realized that it is never the reinforced concrete hospital that protects the world, but every doctor with a sincere heart.