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"Crazy genius" is an enduring topic. Literary and artistic creation is the crystallization of human spiritual civilization, and literary and artistic masters are symbols of the nobility of the human spirit. However, there is a special group of masters in history who had unfortunate childhoods, poverty, disorder, alcoholism, madness, dissoluteness or independence from the world. They suffer from mental disorders such as schizophrenia, personality disorders, bipolar disorders, anxiety disorders, substance-related and addiction disorders, etc. Their lives and works are products of the two-way pull between pain and redemption. This book focuses on 21 Chinese and foreign literary masters with mental disorders, including Dostoevsky, Nietzsche, Van Gogh, Natsume Soseki, Woolf, Eileen Chang, etc., Through detailed pathological methods, sorting out their life histories, analyzing mental disorders, and then comparing the content and style of their important works to deeply explore the relationship between mental disorders and creation. By tracing back the survival and creative evolution of many Chinese and foreign masters, and with the help of their delicate and superb creative skills, this book shows the unique creative world and inner struggle of people with mental disorders, and reveals the diverse physical, mental and social significance of mental illness. It is a book that is both academic and readable. It hopes to provide some inspiration to psychiatric researchers, art therapy workers, people suffering from mental disorders and psychology enthusiasts, and to reduce the public's fear and stigma of mental disorders.