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Xiao Yifeng, a handsome and free-spirited obstetrician and gynecologist at Jiaqing Hospital, received Meng Qingqing, a young mistress from a wealthy family. Because Meng Qingqing suffered from congenital heart disease, she had to stay in the hospital for a long time to wait for the birth of her fetus. Meng Qingqing fell in love with Xiao Yifeng due to the abuse by her parents-in-law and her husband Kang Haihan was busy with work and had no time to take care of her. Xiao Yifeng broke up with his girlfriend Huo Fei. But Meng Qingqing died of dystocia during childbirth. Xiao Yifeng was heartbroken and suddenly fainted while taking a bath. When he woke up, he found that he had arrived in the capital of the Qing Dynasty, and met and fell in love with Lu Qingshi, who looked exactly like Meng Qingqing. In an accident, Xiao Yifeng rescued the visiting princess Mu Ya. Mu Ya fell in love with her and framed Lu Qingshi in order to get Xiao Yifeng. However, Zhang Gunan, the general's son who wanted to become the prince's consort, repeatedly obstructed him. In the end, Lu Qingshi committed suicide and Xiao Yifeng was devastated again. When he woke up, he found Huo Fei who had been by his side...

Eight nursing college students with different personalities experienced adventures and emotional changes in different departments during their one-year hospital internship, from their first love and strong curiosity to their gradual maturity and separation. Along the way, they experienced bitterness and misunderstandings, overcame many difficulties together, and formed a deep sisterly relationship.