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This book is a historical work focusing on the cross-civilizational exchanges between China and Spain in the 16th and 17th centuries. The book is based on the route from Spain through the Americas to the Philippines and the southeastern coast of China. It describes the grand trade of large sailing ships traveling back and forth between Fujian and Mexico based on the regularity of monsoons and ocean currents. The "silk-silver convection" represented by silk, porcelain and silver has not only reshaped the trans-Pacific economic structure, but also driven in-depth interaction between people, concepts and culture. Missionaries, immigrants and even pirates jointly participated in building an ocean world full of competition and cooperation, blending and mutual learning. This book breaks the traditional narrative of Asia's role in the globalization process, reveals the influence of Chinese culture in the formation of the East Asian cultural circle, and provides a new perspective for understanding early globalization and its historical impact.