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Manuel and Gregorio are good brothers. They each got a night buffalo tattoo to symbolize their inseparable friendship. But after Manuel had an affair with Gregorio's girlfriend and sister, their relationship gradually soured. Gregorio eventually fell into madness and committed suicide with a gun. After the tragedy, Manuel wanted to get his life back on track, but relatives and friends around him believed that he had concealed the cause of his best friend's death. At the same time, Gregorio's ghost lingered, leaving a box of letters full of revenge and torturing Manuel with a series of crazy words. Manuel begins to have a mental breakdown. Will he also follow the crazy path of his best friend and end his life in the same way?

In a remote town in Mexico, the naked body of a girl was discovered. Rumors immediately spread and Ramon was mistaken for the girl's boyfriend. Ramon also recognized this relationship by mistake and fell in love with the dead girl in his fantasy. In the drunken gossip, everyone unanimously believed that the Gypsy was the murderer of the girl. Under the instigation of everyone, Ramon decided to use the most primitive and direct way to regain his dignity and prove his love for the girl. A revenge of strangers begins.