A pair of mysterious sisters live in seclusion deep in Qixia Mountain. The elder sister Ning Zhiwei has unparalleled medical skills but is suffering from cold poison. The younger sister Ning Zhao is naive and does not know that she has the blood of medicinal spirits.
When Ning Zhiwei, in order to save Gu Xingzhi, who seemed to be his former savior, used the only herbal medicine that could cure his hidden disease, the gears of fate began to turn. The hidden exploration in Gu Xingzhi's eyes after he woke up, the strange golden pupils of Bai Yi, the traitor in Yaowang Valley, the hot ancient tattoo on the wrist of Orion boy Zhou Ziling... Everyone who approaches them has ulterior motives.
"Sister, why does the wound of the little rabbit I touched heal on its own?" "Zhaozhao, remember, never bleed in the moonlight."
As Ning Zhao's bloodline gradually awakens, Ning Zhiwei discovers an even more terrifying truth: they are not biological sisters, but the "containers" and "keys" in the Yaowang Valley's thousand-year plan. When the blood moon comes, Bai Yi activates the soul-changing formation, and Ning Zhiwei is willing to use his body as bait: "In the next life, I will be your sister to protect you."
Gu Xingzhi cut his heart as a guide, and Zhou Ziling's eyes were destroyed, just to give Ning Zhao a glimmer of hope. When the last sacred herb bloomed in the forbidden area, the fate of the three people had already been tightly entwined by the spirit pattern - it turns out that the most precious medicine has never been the power of blood, but the heart that is willing to die for each other.
Intention: The best is medicine, sincerity can heal - the real salvation lies not in the power of blood, but in the courage to be willing to break oneself for the one you love.