A little spider picked up a little black spider, and then it was eaten in one bite. The story of the little spider in the movie universe and the venom-infused black spider in the comic universe.
The timeline is after Avengers 3 (modify the world line! Thor made no mistakes and successfully defeated Thanos, which fulfilled my little wish!)
Black Spider: I am a straight man and don't want to fall in love.
Little Spider:......
Later
Black Spider: It smells so good!
Tony's dad: You crawl for me!