At the end of the Yuan Dynasty and the beginning of the Ming Dynasty, Yuan Mingzong was poisoned by his younger brother Yuan Wenzong. His eldest son, 12-year-old Tuohuan Tiemu'er, was exiled and narrowly escaped an accident. He was rescued by the heroine and his teacher, and he never forgot the heroine. The heroine, Ming Qingqing, was separated from her parents when she was young. She was rescued and raised by the medicine sage Qin Tuo. Due to the snow and cold, she suffered from cold illness since she was a child. Later, she practiced the Li Shui Jue improperly, and the cold poison penetrated into the meridians. Fortunately, she met Xunyangzi, an expert from outside the country, who taught her the Yi Jin Jing and the innate skills to turn bad luck into good luck. The male protagonist Nangong Heng is the young master of Lishui Villa, the best village in the world, and his teacher is Qin Tuo's senior sister Chu Yuren. Chu Yuren was unwilling to live in seclusion because Qin Tuo refused, so she deliberately concealed the key to the Lishui Art from Qin Tuo, which indirectly caused Ming Qing to almost die. Later, she and Qin Tuo resolved their feud and got married. Tuohuan Tiemuer succeeded to the throne after many twists and turns, and became Yuan Huizong, the last emperor of the Yuan Dynasty. After Yuan Huizong took control of the government, he made great efforts to rule and kill powerful ministers in order to revitalize the current affairs. However, the Yuan Dynasty was exhausted and natural disasters occurred frequently. Huizong was repeatedly rejected by the Ming Dynasty, so he became dissolute and deceived people to practice the art of male and female cultivation. Ming Qing, Nangong Heng and other heroes in the world first helped Peng Yingyu resist the tyranny of the Yuan Dynasty, and then helped Zhu Yuanzhang to seize the country. During this period, love and hate were separated, grievances were infatuated, and even unparalleled achievements caused a bloody storm in the world.