In 4050, a group of people who were lucky enough to survive the "Nirvana Project" more than 2,000 years ago encountered a more desperate crisis. The alien "sorrows" did not become extinct due to changes in time and environment. Instead, they continued to evolve and formed various categories. Those who survived actively sought survival and continued to fight, but in the end they could not escape death. In a moment of despair, Dr. Smith asked his disciple Huai Ye to return to 2020 to find the source of species mutation, eliminate it from the source, and prevent human extinction. However, the turbulence of time and space caused Huai Ye to accidentally possess a 17-year-old boy with the same name and his parents who died mysteriously in 2018. Therefore, while Huai Ye was investigating the cause of species mutation, he was also involved in a turbulent struggle, encountering endless dangers in the past and the future...