Two orphans were adopted and trained by an organization called "Cloud Atlas" and became each other's only support. They had a rough life. One managed to escape the organization and gained freedom and became famous, while the other became the secret executor of the organization and was licking blood at the tip of a knife. More than ten years later, the two meet again, carrying their own secrets and hiding behind false identities. They test each other, confirm each other, use each other, fall in love and kill each other. However, everything is just part of the puzzle set up by the organization. Their fate has long been out of their control...