With the skill of the female doctor Ming Fei, she developed the Longevity Pill herself. She has experienced the downfall of generations of dynasties. In the long river of more than 1,800 years, there are many love-hate entanglements that she has never been able to overcome. And why did the man named Yishu appear repeatedly in her life? Every encounter seemed to have been destined several lifetimes ago. . . . .