Unknown masters appeared in Italy's unknown small-scale drugstore - Sitali, and attacked Vongola several times. What's the reason? Soseki Aoki, the murderer who killed thousands of people, returns, and Balian defectes after becoming BOSS? Can the grudges of one life be resolved in the tenth life? A powerful enemy suddenly attacks and all the guardians are destroyed? The peak showdown on the isolated island, the ultimate state of the ring, the quadratic box opening, V. C.... Strong enemies are constantly coming! Reinforcements are coming! Understanding through hardship, rebirth and chaos in desperate situations are about to break out. . . . .