At the beginning of the 16th century, the Papal States controlled the Italian peninsula through the dark organization "Brotherhood of the Holy Sword". The former assassin Livia awakened during a mission and tried to escape the organization. However, in a political marriage in Florence, she accidentally married Isabella, the daughter of a Jewish banker. In order to protect the family, Isabella lurked next to Livia with her true identity. Two women with very different identities went from being suspicious of each other to trusting each other in life and death. At this time, the Papal States attempted to annex Florence, and there was an undercurrent of competition for the position of Doge of Venice. Livia and Isabella met the Venetian admiral and humanist scholar, and the four formed an alliance. In the financial secret war and the flash of swords, they gradually disintegrated the Brotherhood's conspiracy. In the end, Livia cut off the shackles of the Holy See and gained freedom, and Isabella broke prejudice and gained dignity. The two embraced each other at dawn in Venice and embarked on a new life together.