Yanzhou Medicine Master Shu Yao is actually an abandoned daughter of her family who was murdered by her sister five years ago and pushed off a cliff. On the night of falling off the cliff, Qin Yuan, the Qilin God, was attacked by his poison, and the two accidentally got entangled. When Shuyao was giving birth, the demon clan attacked her. The eldest daughter Xiaoyan desperately set up a barrier and her whereabouts were unknown. Shuyao only survived with her youngest daughter Xiaomiao. During the past five years, Shu Yao treated Xiao Miao for cold illnesses, while Qin Yuan also searched hard for his eldest daughter Xiao Yan. Until Shu Yao stepped into the palace to practice medicine, the twin sisters were accidentally hugged by the wrong person. The twins teamed up to recognize each other, and finally solved the five-year estrangement and mystery between their parents.
