Umbrella Corporation, which studies biological weapons for the military, has a huge research center called the Hive underground in Raccoon City. Due to an accident, airborne biochemical weapons were leaked. The computer system "Red Queen" responsible for the security of the hive activated emergency measures, which resulted in the death of hundreds of staff... Four hours later, Hive security guard Alice woke up at the exit of the hive and lost her memory due to the sleeping gas. A special team ordered to shut down the Red Queen came here, together with Alice and Anderson, who claimed to be a police officer.