Shen Zhiyi, a top modern surgeon, was reborn in a car accident as an orphan from an abandoned drug store in the Republic of China. She was responsible for the "Book of Life and Death" system - saving people can be exchanged for key information. After accidentally saving a warlord's wife, she was involved in the vortex of conspiracy in the concession. She uses her medical skills as an edge to break the strange rules and myths: if you open the door in the middle of the night, you will die, if you prescribe medicine, you must sign a life and death certificate, and the consultation fee must be exchanged with secrets. In order to find out the truth about the murder of her biological mother, she dealt with warlords, newspapers, and churches, overturned the black market murder case with a piece of prescription, used acupuncture to save the imprisoned underground party, and finally restored the dignity of women in troubled times with the attitude of a doctor who "does not sell her life, only saves her life." Every time she takes action, she tears apart the rotten rules beneath the surface respectability of the Republic of China.