Jiang Wan has been known as a disaster star since he was born. He is born with a devouring constitution that will unconsciously suck away the luck of everyone around him, causing constant collisions at best, and exhausting life span at worst. All members of the Jiang family despised her and regarded her as a stain on the family. The eldest brother Jiang Chen even secretly colluded with Gu's Biological Group and wanted to use her for live experiments.
Only her childhood sweetheart Lu Jing, who knew everything since he was eight years old, voluntarily modified his genes and became the lucky donor to match her. For more than ten years, he had suffered misfortune and lost his life due to Jiang Wan time and time again, but he never avoided it and silently endured all the bad luck, just to let her live peacefully.
Jiang Wan has been deliberately alienating Lu Jing, fearing that she will kill him, until a dusty experimental file reveals the truth: Shen Ruoyun, her mother, led the "lucky transfer" gene project back then, setting up many back-ups to protect her daughter, while the Gu family attempted to plunder luck-controlling genes and build a luck trading industry chain to harvest ordinary people.
The Gu family laid a dragnet, kidnappings, plots, sieges and killings followed one after another, and even exposed the tragic past of their mother. Jiang Wan has completely awakened to the power of luck control, and can freely absorb, release, and coordinate everyone's fortune; Lu Jing no longer gives blindly, and the two find a solution to genetic symbiosis - no more one-way loss, each other is a source of energy, and they share life span and good luck.
They join forces to smash Gu's and Jiang Chen's conspiracy, expose the dark truth about human experiments at that time, and set up a charity foundation to adjust the fate of the people at the bottom. The unlucky daughter and the lucky horse who once dragged each other down finally stay together for a lifetime and control their own destiny and that of everyone in the world.