Su Yunwan, a modern female forensic doctor, accidentally transformed into a sickly concubine of the Yushi Mansion and was forced to marry Xiao Jinglan, the rumored moody Prince of Qi, for her eldest sister. On her wedding night, she used professional techniques to resolve the poisonous wine crisis, attracting the attention of King Qi. In the court, there is an undercurrent of competition between the prince and King Qi. Su Yunwan repeatedly solves unsolved cases with his forensic skills. From seemingly unrelated cases, he gradually pieced together the truth about the unjust death of his biological mother ten years ago. The "witchcraft case" that destroyed her family actually implicated the core secret of the change of imperial power.
From Xiao Jinlan's initial suspicion and testing to working together to investigate old cases, the relationship between the two heated up in the test of life and death. As the truth approaches, Xiao Jingheng, the mastermind behind the scenes, sets up a serial killing scheme. Su Yunwan conducted an autopsy to track down the murderer, made poison to counterattack, Xiao Jinlan built a plank road openly and secretly infiltrated Chen Cang, and finally exposed the prince's shocking conspiracy to kill his father and usurp the throne with irrefutable evidence in the court. When the dust settled, Su Yunwan gave up the opportunity to return to modern times and chose to stay in this world where he was.