Poison doctor Zhu Yuan travels to the edge of the Great Yao Dynasty with his full pharmaceutical and business skills, and meets Zhao Heng, the emperor's uncle whose power has been reduced. The two work together to stock up on scarce medicinal materials and people's livelihood supplies through advanced knowledge, and gradually build a complete infrastructure system. In the turbulent workplace business war in the fief, they defeat the plans of many opponents, finally stabilize the foundation of the fief, and break out of their own business territory.
