Shen Qingci, an heir to a modern family of doctors and poison experts, transmigrates after a plane crash into the body of Su Qingci, the poisoned, overweight legitimate daughter of the prime minister of the Great Sheng dynasty. The original owner was poisoned by Concubine Liu for eleven years, weighed 280 jin, had her meridians sealed, and had a bedridden mother.
She awakens the Nine Heavens Spirit Ruins, a portable realm containing a spirit spring, spirit fields, and a bronze alchemy furnace. Using the array flames of the Spirit Ruins, she takes up medicine and poisoncraft again, fighting back as she works to purge the poison. The spirit spring flushes out toxins, silver needles unblock her meridians, and pills temper her body. In three months, she is transformed from head to toe.
On the night of the full moon, Ye Chenyuan, the young lord of the divine clans, covered in blood, tumbles over the wall into the side courtyard. He has been afflicted with the Dragon Clan's Soul-Eroding Curse for twenty-two years and has been told he won't live past twenty-five. He is also bound by a political engagement to a princess of the Phoenix Clan. The two strike a deal: she will cure him, and he will keep her safe.
As she heads north from the prime minister's side courtyard, she discovers that she has been caught up in more than a simple revenge plot: six divine clans and a century-spanning struggle for power. The Dragon Clan's hidden pawns have infiltrated the northern lands of the Ye Clan, the earth marrow mines, and even the circumstances surrounding her great-grandfather's death. All of it is part of the same game.
The poison she must cure isn't only the one within her body. She must also find a way out of a deadly trap spanning all six clans.