In her previous life, she was a world-famous and deadly poisonous doctor, capable of healing people and destroying cities with her poison. However, she died tragically because she mistrusted her closest relatives and friends. When she opened her eyes again, she became Su Wantang, the sick and frail daughter-in-law who could be bullied by everyone in the general's palace. Not only was she framed and stigmatized by her concubine, but her fiancé also broke off the engagement in public, making her the laughingstock of the entire capital. But no one knew that this seemingly weak body contained a cold soul crawling back from the mountain of corpses and sea of blood. She wields silver needles and possesses poison skills. She cures herself first, then settles old scores. She fights concubines and scumbag men, investigates the truth behind her mother's death, solves the mystery of the court, and moves from the deep house to the center of power step by step. Everyone thought she was just an orphan girl with some medical skills, until she rescued the prince, killed powerful officials, and defeated the enemy with poison. The whole court knew that this young lady was not a soft persimmon who could be manipulated, but a peerless poison doctor who could change the world. Just when her revenge was about to be fulfilled and old grudges were about to be extinguished, the regent, who seemed cold and taciturn, but actually set up a trap to protect her, finally broke away from the disguise of restraint and dragged her into a deeper maelstrom of intrigue and emotion.