Shen Nian was taken back to Shen Mansion by his biological father as a "drug guide", but he discovered that there was a shocking secret behind the poison given to his aunt. Relying on the wordless medical books left by her mother and her "qiyun acupuncture" skills, she stepped from the abandoned daughter in the back house to the palace. The queen mother of the current dynasty was poisoned, the sixth prince was suffering from the "hundred-day red" strange poison, and the previous dynasty's imperial physician ordered all the cases of injustice - all the clues pointed to the same pair of masterminds. Shen Nian uses the silver needle as a blade to save people, establish authority and break the situation in the cracks of power and intrigue. She not only wanted to cure the chronic diseases of an era, but also to open up a path for women all over the world where "healers are without distinction". This is the mutual redemption of the benevolence of the doctor and the power of the emperor. It is also a female epic that changes the world with medical skills.