In the fifteenth year of the Republic of China, Shen Qingru, a female doctor who had returned from studying abroad, met Gu Yanzhi, a taciturn young man from a Chinese medicine shop, while treating the wounded at the mission hospital. She believes in the science of Western medicine, while he adheres to ancient prescriptions that have existed for thousands of years. As the war approached Shanghai, he handed over a pack of angelica: "In this world, there must be someone who remembers the way home."