Intern Jiang Chen was smoking on the rooftop of the hospital during the night shift and was struck by a thunderbolt. After waking up, he found that he had obtained a pair of "yin and yang eyes" that could see "evil energy". He can see through the meridians of the human body and see the abnormal energy entrenched in the patient's body. With these eyes, he rescued a car accident victim who was sentenced to death with only a silver needle, and therefore was targeted by a mysterious underground organization "Qihuang Society".
Immediately afterwards, the new head nurse Shen Qingyu revealed to him his mother's secret: his mother Jiang Yuehua was not an ordinary woman, but the Feng Shui consultant of the Shen family twenty years ago. She disappeared because of a "Taisu Acupuncture Classic" that could "defy the heaven and change the fate". In order to find out the truth behind his mother's death, and to clear out the "evil seeds" planted in his body, Jiang Chen was forced to deal with the "Qihuang Society" who wooed him and Shen Qingyu who asked him for help. During the day, he was an unknown intern in the hospital, and at night, he used his celestial eyes and the ancestral "Tai Su Acupuncture Sutra" to solve weird Feng Shui murderous situations one after another, relieving the pain of the cursed rich and the patients eroded by evil spirits. As the truth deepens, he discovers that the disappearance of his mother, the coma of the old Shen family, and the mastermind behind all events point to the ultimate villain named "The Poison King". Jiang Chen must combine ancestral acupuncture techniques with the power of the heavenly eye to grow from an intern doctor to a chess player who can influence the pattern of Feng Shui.