Rong Zhi is the daughter of the imperial physician Ling. Because of her stepmother's plan, she entered the palace to replace her sister and marry the frail emperor Ji Heng. On the surface, the emperor coughed up blood and was bedridden, but in fact he was poisoned by a strange poison and was full of murderous intentions towards Rong Zhi. He thought she was an informant sent by the Queen Mother. With her medical skills, Rong Zhi discovered that the emperor's poison was not innate but caused by long-term drug use. She used detoxification as a bargaining chip to gain short-term benefits. Temporarily safe; the Queen Mother and the powerful minister Wei Guogong set up multiple assassinations, Rong Zhi rescued the poisoned palace maid, subdued the secret guard, and got acquainted with the old imperial doctor in the palace and learned the secret of the palace incident ten years ago; the emperor secretly trained a dead man, both testing and relying on Rong Zhi, her several treatments made him loose his murderous intention; Rong Zhi exposed the poison and framed the case by Wei Guogong at the Queen Mother's birthday banquet, and the emperor obeyed The emperor secretly investigated and found that Rong Zhi was not a pawn of the Queen Mother, but was secretly clearing obstacles for her; Rong Zhi reached a deal with the emperor, and after she was detoxified, the emperor let her out of the palace, but the border was in danger, and the emperor's chariot was ambushed during a personal expedition. When Rong Zhi was treated by the army, he discovered the emperor's throat scar and the late emperor's will; the emperor actually As an orphan of the previous dynasty, Rong Zhi was secretly replaced by the Queen Mother, and Rong Zhi faced a torn relationship and loyalty; the powerful ministers teamed up with the rebels to force the palace, and Rong Zhi tried her own medicine to prepare the antidote. The emperor repented and led his troops to counterattack; in the end, the emperor ascended the throne and recognized his ancestors and returned to the clan. Rong Zhi became the queen but did not want to be trapped in the harem, and promoted medical reforms. The two went from killing each other to supporting each other in life and death, and jointly created a prosperous age.