Cancer expert Song Jian opened his eyes and turned out to be the "drug dregs" in Jinyiwei during the Zhengde period of the Ming Dynasty - a useless man who was fed hundreds of highly toxic elixirs but did not die. He just wanted to survive in the Pharmacy Department until an intact mummy was placed in front of him: all the blood in the deceased's body disappeared out of thin air, but there was a still beating heart embedded in the chest. When the black heart exploded in his palm, revealing a golden needle engraved with the word "immortality", he was shocked to realize that he had already been involved in the conspiracy. The only one who believed in him was Shen Zhiyan, the first female officer of the Ministry of Punishments - a crazy woman who dared to break into the Jinyiwei Prison in order to conduct an autopsy and investigate the case. A useless person who is invulnerable to all poisons, a female official who cannot be tolerated in the world, is trying to unravel a mysterious case that spans twenty years and uses the flesh and blood of living people to refine "immortality" in the cracks between the Jinyi Guards, the Medicine Refining Hall and the numerous shady scenes.
