Lin Yi, an ordinary Chinese medicine student in Jiangbei City, has been able to see things that ordinary people cannot see since he was a child. Before his death, his grandfather gave him a broken ancient book "Yin Yang Ghost Doctor", and his fate was completely changed from then on.
During the day, he is a student studying hard in medical school; at night, he shuttles between the yin and yang realms, using his medical skills to save people and his magic to exorcise evil spirits. When the strange shadow of death enveloped Jiangbei City, and when the evil spirits that had been sleeping for thousands of years began to awaken, Lin Yi discovered that he was actually the last descendant of the ancient Onmyoji lineage.
Ghost babies seeking their lives, zombies being resurrected, evil spirits possessing people, evil soldiers crossing the border... Behind each of these bizarre events lies a shocking conspiracy that has lasted for eight hundred years. And all he can rely on is the incomplete ancient book and the mysterious power in his body that sometimes wakes up and sometimes falls asleep.
On this yin and yang road, he is neither a god nor a demon, but a ghost doctor walking between life and death. But this time, he was determined to break his fate and change his destiny.
