In the fifteenth year of Qianlong's reign, the one-eyed doctor Huang Yuanyu's whereabouts were exposed due to the case of a bewitched lady from Haifu. Thirty years ago, his grandfather tried to save him from being blinded by a poison, leaving behind the mystery of "Thirty-Six Children". Huang Yuanyu used his body to lure Gu to save people, and found that he was actually the "Tianshu" of the formation - the thirty-sixth sacrifice that Emperor Yongzheng used to renew the formation forty years ago. Forces from all sides surfaced: Wang Shizhen, the former medical doctor of Taiyuan Hospital, taught him the method of breaking the formation, mysterious Zhou Jimin passed the list on his orders, Haiwang, the head of the Ministry of Internal Affairs, Fu Heng, the supervisor of Qintian, and Hongxiao, the prince of Yi, all had their own agendas. Huang Yuanyu went to Yunnan to search for the "Keys to Breaking the Formation" and learned that the formation was about to be opened, the prince was the eye of the formation, and the lives of thirty-six children were in danger. During the winter solstice in the underground palace, he pierced thirty-six acupoints of his own body with golden needles, drawing the formation energy into his body. He became completely blind, and finally broke the formation and saved the children. Later, he retired to Jishengtang, where he lived countless lives with his art of listening to pulses. He refused to be granted a title by the imperial physician, and died in the sound of falling leaves from the locust tree.