At the end of the Southern Song Dynasty, the imperial court was corrupt, surrounded by powerful enemies externally, and endless party feuds internally. In a surgical accident, modern surgeon Ling Yun's soul traveled to Su Yunqing, a descendant of a down-and-out doctor in Lin'an Prefecture of the Southern Song Dynasty. Faced with the plight of a poor family and the backward medical environment in ancient times, Su Yunqing (Ling Yun) relied on modern medical knowledge to survive in the market. He improved the stethoscope, made simple surgical tools, and used "empirical diagnosis and treatment" methods to treat tuberculosis patients who were regarded as "strange diseases", and he first showed his talents. Li Xuanzhen, the son of the judge of Taiyuan Hospital, regarded him as a thorn in his side and planned to frame him. However, Su Yunqing used his superb medical skills to resolve the crisis, and instead won the appreciation of some enlightened officials. When dealing with a small-scale plague, Su Yunqing introduced modern epidemic prevention concepts such as isolation and disinfection. Although he was opposed by conservative doctors, he successfully controlled the epidemic and became famous. He got acquainted with Chen Liang, a scholar of the Zhu Xi School who advocated "studying things to gain knowledge", and jointly discussed the relationship between medicine and science. With the support of Taiyuan Hospital, Su Yunqing established China's earliest medical laboratory and trained a group of doctors who mastered the basics of modern medicine. In the end, he shocked the government and the public with a successful "laparotomy" operation in front of the emperor, and gained the power to establish a "new medical bureau", bringing unprecedented innovation to the Chinese medical system.