: The heroine Shen Zhiyun was originally the eldest daughter of the Duke of Zhenguo. She had outstanding medical skills and unparalleled resourcefulness. However, because she failed to help the prince pacify the border troubles, she was feared by the emperor, framed by the prince, and her husband (the third prince of the dynasty, Xiao Heng) personally handed him poisoned wine and a silver knife to cut out his eyes. When she was reborn and returned to her wedding, she coldly exposed the poison in Hexin wine, burned the marriage certificate, and took the ancestral "Qing Sang Fragments" to defect to Xiao Yan, the prostitute in the north - the "waste" who was despised by the whole court and was lying on the bed coughing up blood. After that, she entered Taoism with medicine and controlled power with poison. She built a righteous warehouse in the north, set up a medical school, and trained secret guards to help Xiao Yan clear out the traitors in the Proton Mansion and reverse the situation of the government. Xiao Heng ascended the throne and became the emperor and pursued his wife frantically, but was repeatedly crushed: She saved his life but he suspected her of poisoning, she retreated thousands of miles and he issued an edict to denounce her as a "female chicken Si Chen". In the end, the truth was revealed - the secret letter of collaboration with the enemy was forged by Xiao Heng's biological mother, Concubine Shu, and the silver knife that cut out his eyes was handed out tremblingly but he did not dare to raise his eyes; and she had mixed the antidote into his daily decoction for three years, and was only willing to let him live when he confessed in person.