The medical fairy had a premonition that his time was coming, and ordered his disciples to go down the mountain to practice, and to select disciples to pass on the mantle based on the standard of promoting the spirit of medicine. Li Zhan, who had four hundred yuan in his pocket, unexpectedly shared a room with Azhen, a bartender who had a rough life experience. From the initial conflict to the gradual trust, they formed a deep bond. Li Zhan practiced medicine on the street to no avail, but he repeatedly relied on his medical skills and skills to protect A-Zhen, refused to be wooed by gangs, and stuck to his original intention of medicine. In order to help Zhen realize her dream of settling down, Li Zhan agreed to treat gangster Jiu Ye, but found out that Jiu Ye had been poisoned by his rival Qi Shu, and that his senior brother Li Qiang colluded with Qi Shu to seize power and used the "Nine Needles to Return Yang" to murder Jiu Ye.