Shen Du is reborn in the Gu world with memories of his previous life. Cold and indifferent, he'll do whatever it takes to stay alive. The White Snake Gu girl, Bai Suzhen, enters his dark world. Amid the brutal art of refining, raising, and using Gu, the human and the snake go from trying to kill each other to falling in love, and from selfishness to protecting one another. In the end, they become peerless true demons and defy fate.