Chen Mo, a college student, was framed by business tycoon Zhao Tianze because his parents discovered the secret of the ancient god-slaying inheritance and the seal of the evil god. He was charged with parricide and was injected with drugs and sent to a mental hospital, where he was humiliated. When he was about to die, he activated the "God-level God-Slayer Sign-in System" and awakened the blood and memory of the ancient God-Slayer.
With the help of system rewards, Chen Mo killed the enemy's minions in the hospital, exposed the dean's conspiracy, and got acquainted with the previous generation guardian "Old Ghost" who disguised himself as an old man sweeping the floor. He learned that he was the reincarnation of the God-killing leader who sealed the evil god thousands of years ago, and that Zhao Tianze was actually the evil god's lackey, trying to unseal the evil god and cause trouble in the world.
Chen Mo teamed up with Su Wanqing, the female captain of the Alien Management Bureau who came to investigate the evil incident, exposed Zhao Tianze's identity as an evil cultivator and killed him in public, obtained the first artifact fragment "Guardian Seal", and integrated the Jiangcheng cultivation world. However, Zhao Tianze's death triggered a deeper crisis - the evil god's four guardians awakened, and seal nodes in many places across the country were loosened.
In order to cope with the overall crisis, after repelling the "Black Wind Guardian" who came to intercept and return the aid to resolve the evil tide in Jiangcheng, Chen Mo, along with his master Lao Gui and his comrade Su Wanqing, went to the capital at the official invitation. His new journey is to unite the cultivation forces across the country, form an alliance, collect artifact fragments, fight against the fully resurrected evil god forces, and protect the peace of the world.
